Why in News?
A nationwide study under the Indian Pediatric Oncology Group (InPOG) reported 94.5% five-year survival in childhood cancers.
Description:
About the Registry:
| Feature | Details |
| Nature | Nationwide Childhood Cancer Registry |
| Cohort Name | Indian Childhood Cancer Survivorship (ICS) Cohort |
| Coordinating Body | Indian Pediatric Oncology Group (InPOG) |
| Publication | The Lancet Regional Health – Southeast Asia (Feb 2026) |
Key Survival Outcomes:
Five-Year Outcomes (from diagnosis):
- Overall Survival (OS): 94.5%
- Event-Free Survival (EFS): 89.9%
Among Survivors Followed ≥2 Years After Treatment:
- Overall Survival: 98.2%
- Event-Free Survival: 95.7%
Event-Free Survival (EFS): Percentage of patients without relapse, progression, or death during follow-up.
Most Common Childhood Cancers:
| Cancer Type | Share | Explanation |
| Acute Leukemia | 40.9% | Cancer of blood-forming tissues; affects white blood cells and bone marrow. |
| Hodgkin Lymphoma | 12.9% | Cancer of the lymphatic system marked by presence of Reed–Sternberg cells. |
| Bone Tumours | 8.4% | Malignant growths originating in bone tissue (e.g., osteosarcoma). |
Late Effects Identified:
- Despite high survival rates, childhood cancer survivors may develop long-term complications such as hormonal and growth disorders, fertility issues, cardiac problems, learning and cognitive difficulties, and psychosocial challenges.
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