Gene-Silencing Nanomedicine for Breast Cancer Treatment (Source: PIB)

Context:

Scientists from Agharkar Research Institute, Pune, have developed a biodegradable nanocarrier platform for targeted gene therapy in breast cancer. The strategy aims to silence cancer-driving genes and inhibit tumour growth with reduced systemic toxicity.

Explanation:

• Nanomedicine uses nanoscale materials (between 1 and 100 nanometers) for diagnosis, drug delivery and targeted therapy.
• In cancer treatment, nanocarriers can deliver therapeutic molecules directly to tumour cells.
• Gene silencing means reducing or blocking the expression of disease-causing genes.
• It can target cancer survival pathways and prevent tumour cells from growing or spreading.
• Precision medicine focuses on customised and targeted treatment instead of broad systemic therapy.
• Conventional cancer therapies may affect healthy cells, causing toxicity and side effects.
• Biodegradable nanocarriers are useful because they can break down safely inside the body.
• The research is linked to breast cancer, targeted gene therapy and tumour suppression.
• Agharkar Research Institute, Pune, is an autonomous institute under the Department of Science and Technology.

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Gene Silencing Therapy and Targeted Cancer Treatment