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Platinum-Based Chemotherapy Drug Shortage and India’s Medicine Supply Challenge (Source: Down To Earth)

Context

Recently, patients and hospitals across India reported shortages of cisplatin, carboplatin and oxaliplatin, important platinum-based chemotherapy medicines. Disrupted platinum supplies, rising input costs and controlled medicine prices have affected domestic production and timely cancer treatment.

Platinum-Based Chemotherapy Shortage and Drug Security

Explanation

  • Cisplatin, carboplatin and oxaliplatin are platinum-based chemotherapy medicines for cancers of the lungs, head and neck, ovaries, cervix, testis and digestive system.
  • They form cross-links in the cancer cell’s DNA, blocking replication and causing cell death.
  • India makes the finished medicines but imports platinum and related active pharmaceutical ingredients (APIs); South Africa is the leading producer, with supplies also routed through the UAE and Tanzania.
  • West Asian conflict, disruption around the Strait of Hormuz and costly logistics have restricted raw-material availability.
  • Platinum prices also rose on demand from the jewellery, automobile, electronics, semiconductor and clean-energy industries.
  • The National Pharmaceutical Pricing Authority (NPPA) fixes ceiling prices under the Drugs (Prices Control) Order, 2013, and in June 2026 raised those of cisplatin and carboplatin by 50% for six months.
  • Remedies include diversified suppliers, domestic API capacity, shortage monitoring and buffer stocks — an inexpensive medicine helps no one if it is unavailable.

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